Already aligned boxes in the forms collapsed After some days ASP.Net

My forms Designed in ASP.Net With bootstrap and CSS. After few days boxes in the not aligned properly while debugging.

Same source code and Design working properly in some systems. After few days that working system forms also getting collapsed,

I don't know why this happen.Please help.

Any updates will occur automatically in bootstrap .?? or We need to Install any packages for getting this alignment works properly??

Please help..

enter image description here