python array size error only occurs in binary release but not when running from source

I have a python app that can be run from downloaded binary release or from source. When I run the .exe file, I get the following error from trying to load a very large image stack:

array is too big; arr.size * arr.dtype.itemsize is larger than the maximum possible size

However, when I run this code from source (from CMD or from Spyder) I do NOT get this error. So I'm guessing this is something with how the developer (sadly, not me) packaged the code or set requirements?

Can I get some thoughts about what to look for since I don't think the issue is in the main code.

How many English words
do you know?
Test your English vocabulary size, and measure
how many words do you know
Online Test
Powered by Examplum